Radioactive arsenic-containing compounds and their uses in the treatment of tumors

232322This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consisting of AsO, AsS, AsS, and a...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Te-Wei, Huang, Chun-Ying, Wu, Ming-Shiuan, Chen, Te-Jung, Chang, Kwo-Ping, Chang, Shiang-Rong, Chyi, Shyh-Yi, Chang, Chih-Hsien, Hsu, Yin-Mao, Fan, Kuo-Hsien, Hsu, Wei-Chuan, Fu, Ying-Kai, Kao, Charng-Feng
Format: Patent
Sprache:eng
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Zusammenfassung:232322This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consisting of AsO, AsS, AsS, and a combination thereof, such that the arsenic element contained in the arsenic-containing compound is converted to a radioactive arsenic isotope; and (ii) recovering the resultant product from step (i).This invention also provides a pharmaceutical composition comprising a therapeutically effective amount of the radioactive arsenic-containing compound and a pharmaceutically acceptable carrier. The pharmaceutical composition can be used in the treatment of tumors/cancers such as hematological malignancies and solid tumors.