Peptides comprising an isoDGR motif

Disclosed herein are peptides which include an isoDGR motif and which selectively inhibit αvβ3 integrin. In some embodiments, the isoDGR motif results from the deamidation of an NGR motif.

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Bibliographische Detailangaben
Hauptverfasser: Corti, Angelo, Curnis, Flavio
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein are peptides which include an isoDGR motif and which selectively inhibit αvβ3 integrin. In some embodiments, the isoDGR motif results from the deamidation of an NGR motif.