Substituted 7,8-dihydro-1H-pyrimido[4,5-B][1,4]diazepin-4-amines are novel kinase inhibitors

Substituted 7,8-dihydro-1H-pyrimido[4,5-B][1,4]diazepin-4-amines are novel kinase inhibitors

Compounds having the Formula (I) are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

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Bibliographische Detailangaben
Hauptverfasser: Gracias, Vijaya J, Abad-Zapatero, Celerino, Djuric, Stevan W, Ji, Zhiqin, Michaelides, Michael R, Stewart, Kent D, Zanze, Irini
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Compounds having the Formula (I) are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.