Process for the preparation of aripiprazole

The present invention relates to an improved process for the preparation of 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-1,2,3,4-tetrahydroquinolin-2-one (Aripiprazole) having dimer impurity less than 0.15%, particularly, the present invention relates to an improved process for the preparation...

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Bibliographische Detailangaben
Hauptverfasser: Deshpande, Pandurang Balwant, Luthra, Parven Kumar, Shanishchara, Ashok Prataprai, Manepalli, Ramesh, Mistry, Dharmesh Balvantrai
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to an improved process for the preparation of 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-1,2,3,4-tetrahydroquinolin-2-one (Aripiprazole) having dimer impurity less than 0.15%, particularly, the present invention relates to an improved process for the preparation of 7-(4-chlorobutoxy)-3,4-dihydrocarbostyril of formula (I) having dimer impurity less than 0.5%