Coronavirus isolated from humans

Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these m...

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Hauptverfasser:	Rota, Paul A, Anderson, Larry J, Bellini, William J, Bowen, Michael D, Burns, Cara Carthel, Campagnoli, Raymond, Chen, Qi, Comer, James A, Cook, Byron T, Emery, Shannon L, Erdman, Dean D, Goldsmith, Cynthia S, Guarner, Jeanette, Humphrey, Charles D, Icenogle, Joseph P, Ksiazek, Thomas G, Meyer, Richard F, Monroe, Stephan S, Nix, William Allan, Oberste, M. Steven, Paddock, Christopher D, Peret, Teresa C. T, Rollin, Pierre E, Pallansch, Mark A, Sanchez, Anthony, Shieh, Wun-Ju, Tong, Suxiang, Zaki, Sherif R
Format:	Patent
Sprache:	eng
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Beschreibung
Zusammenfassung:	Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use.