Indene derivatives and process for the preparation thereof

Indene derivatives and process for the preparation thereof

The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic sy...

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Hauptverfasser: Cheon, Hyae Gyeong, Yoo, Sung-Eun, Kim, Sung Soo, Yang, Sung-Don, Kim, Kwang-Rok, Rhee, Sang Dal, Ahn, Jin Hee, Kang, Seung Kyu, Jung, Won Hoon, Park, Sung Dae, Kim, Nam Gee, Kim, Sun Mee, Mo, Kil Woong, Lee, Jae Mok, Kang, Hye Jung, Lee, Koun Ho, Kim, Jong Hoon, Lee, Jeong-Hyung, Kim, Seung Jun
Format: Patent
Sprache:eng
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Zusammenfassung:The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.