Methods for improving bioavailability of a renin inhibitor

The present invention provides a method for improving the bioavailability of a renin inhibitor, preferably, of a δ-amino-γ-hydroxy-ω-aryl-alkanoic acid derivative, which method comprises co-administering to a mammal, especially a human, in need of such treatment, a combination of a renin inhibitor,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Camenisch, Gian P, Gross, Gerhard, Ottinger, Isabel, Wasmuth, Daniel
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a method for improving the bioavailability of a renin inhibitor, preferably, of a δ-amino-γ-hydroxy-ω-aryl-alkanoic acid derivative, which method comprises co-administering to a mammal, especially a human, in need of such treatment, a combination of a renin inhibitor, or a pharmaceutically acceptable salt thereof, and an efflux protein inhibitor.