Aromatic ether derivatives useful as thrombin inhibitors

Aromatic ether derivatives useful as thrombin inhibitors

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediate...

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Bibliographische Detailangaben
Hauptverfasser: Argade, Ankush Baburao, Goodson, Jr, Theodore, Herron, David Kent, Joseph, Sajan, Lepore, Salvatore Donato, Marquart, Angela Lynn, Masters, John Joseph, Mendel, David, Merritt, Leander, Ratz, Andrew Michael, Smith, Gerald Floyd, Tebbe, Anne Louise, Wiley, Michael Robert, Yee, Ying Kwong
Format: Patent
Sprache:eng
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Zusammenfassung:This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor. An example of a compound of formula (I) is (a).