Susceptibility genes for age-related maculopathy (ARM) on chromosome 10q26

Susceptibility genes for age-related maculopathy (ARM) on chromosome 10q26

Allelic variations in the genes PLEKHA1 and LOC387715 are identified herein as risk factor for Age Related Maculopathy (ARM). A method is therefore provided for identifying a risk of development of ARM in an individual that comprises identification of allelic variations in PLEKHA1 and/or LOC387715....

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Bibliographische Detailangaben
Hauptverfasser: Gorin, Michael B, Jakobsdottir, Johanna, Conley, Yvette P, Weeks, Daniel E, Mah-Fraser, Tammy S, Ferrell, Robert E
Format: Patent
Sprache:eng
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Zusammenfassung:Allelic variations in the genes PLEKHA1 and LOC387715 are identified herein as risk factor for Age Related Maculopathy (ARM). A method is therefore provided for identifying a risk of development of ARM in an individual that comprises identification of allelic variations in PLEKHA1 and/or LOC387715. Related apparatus, such as an array, are identified as being useful in implementing those methods.