Insulator-based DEP with impedance measurements for analyte detection

Disclosed herein are microfluidic devices for assaying at least one analyte specie in a sample comprising at least one analyte concentration area in a microchannel having insulating structures on or in at least one wall of the microchannel which provide a nonuniform electric field in the presence of...

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Bibliographische Detailangaben
Hauptverfasser: Davalos, Rafael V, Simmons, Blake A, Crocker, Robert W, Cummings, Eric B
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein are microfluidic devices for assaying at least one analyte specie in a sample comprising at least one analyte concentration area in a microchannel having insulating structures on or in at least one wall of the microchannel which provide a nonuniform electric field in the presence of an electric field provided by off-chip electrodes; and a pair of passivated sensing electrodes for impedance detection in a detection area. Also disclosed are assay methods and methods of making.