Automatic detection of regions (such as, e.g., renal regions, including, e.g., kidney regions) in dynamic imaging studies

In some preferred embodiments, a system for the automatic identification of cortical and/or medulla regions of the kidneys in renal dynamic studies is provided that includes: a computer module configured to perform principal component analysis on a dynamic sequence corresponding to only one of the kidneys based on a linear combination of the first few component images with coefficients for the principal component analysis as normalization factors.