Pyrazolo[1,5-a]pyrimidine derivatives

Pyrazolo[1,5-a]pyrimidine derivatives

The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent MAPKAP-K2 inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for MAPKAP...

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Bibliographische Detailangaben
Hauptverfasser: Kosugi, Tomomi, Imai, Minoru, Makino, Hiroaki, Takakuwa, Mika, Unoki, Gen, Kataoka, Kenichiro, Mitchell, Dale Robert, Simpson, Donald James, Harris, Clifford John, Le, Joelle, Yamakoshi, Yuko
Format: Patent
Sprache:eng
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Zusammenfassung:The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent MAPKAP-K2 inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for MAPKAP-K2 mediated disorder, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.