Transformed cell harboring DNA or RNA encoding sugar chain synthesizing agent having β1,3-N-acetylglucosaminyltransferase activity

The present invention provides a novel polypeptide having a β1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding...

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Bibliographische Detailangaben
Hauptverfasser: Narimatsu, Hisashi, Sasaki, Katsutoshi, Natsume, Ayumi, Mio, Hiroyuki, Nakagawa, Satoshi, Sekine, Susumu, Togayachi, Akira
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides a novel polypeptide having a β1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding the polypeptide, a process for producing the polypeptide, an antibody against the polypeptide, and a diagnosis method and a medicament for treatment for inflammation, cancer or tumor metastasis using the DNA or the antibody. The present invention is useful for synthesis of a useful sugar chain and diagnosis and treatment for inflammatory diseases, cancer or tumor metastasis.