Substituted aminoethers for the treatment of Alzheimer's disease

The invention provides compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beck, James P, Drowns, Matthew, Warpehoski, Martha A
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.