Prion test

The invention is related to diagnostic methods for detecting transmissible spongiform encephalopathies (TSEs) such as BSE and scrapie and related disease in humans. The invention provides use of guanidine thiocyanate (gdnSCN), or a functional equivalent thereof, for treating at least one sample deri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Garssen, Gerrit Jan, Jacobs, Jorg Günther, Langeveld, Joannes Pieter M, Smits, Marinus Adrianus, van Keulen, Lucien Johannes M, Schreuder, Bram Edward C, Bossers, Alexander
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The invention is related to diagnostic methods for detecting transmissible spongiform encephalopathies (TSEs) such as BSE and scrapie and related disease in humans. The invention provides use of guanidine thiocyanate (gdnSCN), or a functional equivalent thereof, for treating at least one sample derived from a mammal, including humans, for reducing the risk of scoring a false-positive test result in testing the sample for the presence or absence of aberrant prion protein.