Furan or thiophene derivative and medicinal use thereof
1 2 1 2 nm333 12 3 4 The present invention provides a compound represented by the formula (I): [wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, p is 0, 1 or 2, and when p is 2, each R may be the same or different, Ris a hydrogen atom or an op...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | 1 2 1 2 nm333 12 3 4 The present invention provides a compound represented by the formula (I): [wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, p is 0, 1 or 2, and when p is 2, each R may be the same or different, Ris a hydrogen atom or an optionally substituted hydrocarbon group, Ris an optionally substituted aromatic group, Ring A is an optionally substituted monocyclic aromatic ring or optionally substituted bicyclic aromatic fused ring, Xis an oxygen atom or a sulfur atom, Xis a bond, an oxygen atom or -S(O)- (wherein n is 0, 1 or 2), Y is a bond, an oxygen atom, -S(O)-, -C(═O)-N(R)- or -N(R)-C(═O)- (Ris a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, and m is 0, 1 or 2), M, Mand Mmay be the same or different and are each independently a bond or an optionally substituted divalent aliphatic hydrocarbon group, and Mis an optionally substituted divalent aliphatic hydrocarbon group] or a salt thereof, which is useful as a prophylactic and/or therapeutic agent for lipid metabolism abnormality, arteriosclerotic disease and sequelae thereof, diabetes mellitus and the like. |
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