Melusin a muscle specific protein, as a drug target for prevention and treatment of heart failure

Melusin a muscle specific protein, as a drug target for prevention and treatment of heart failure

The present invention concerns non-human transgenic animals as model study for human pathologies, being transgenic for having altered melusin expression. The non-human transgenic animals are to be used as models to study heart pathologies and provide therapies thereof, wherein the heart pathologies...

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Hauptverfasser: Brancaccio, Mara, Silengo, Lorenzo, Altruda, Fiorella, Lembo, Giuseppe, Fratta, Luigi, Tarone, Guido
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Sprache:eng
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creator Brancaccio, Mara
Silengo, Lorenzo
Altruda, Fiorella
Lembo, Giuseppe
Fratta, Luigi
Tarone, Guido
description The present invention concerns non-human transgenic animals as model study for human pathologies, being transgenic for having altered melusin expression. The non-human transgenic animals are to be used as models to study heart pathologies and provide therapies thereof, wherein the heart pathologies are heart failure, and in particular diluted cardiomyopathy.
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title Melusin a muscle specific protein, as a drug target for prevention and treatment of heart failure
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