RAF inhibitors and their uses

V600EThe present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF. The compounds are useful for the treatment of cell proliferative disorders such as cancer.

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Bibliographische Detailangaben
Hauptverfasser:	Lapierre, Jean-Marc, Namdev, Nivedita D, Ashwell, Mark A, France, Dennis S, Wu, Hui, Hutchins, Patrick M, Tandon, Manish, Liu, Yanbin, Link, Jeff S, Ali, Syed M, Brassard, Chris J, Nicewonger, Robb B, Filikov, Anton, Carazza, Rebecca J
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	V600EThe present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF. The compounds are useful for the treatment of cell proliferative disorders such as cancer.