Transgenic rats and spermatogonial stem cells

A transgenic rat expresses a gene of interest, such as EGFP, exclusively in the germ cells of both males and females. From such a transgenic rat one can isolate a line of spermatogonial stem cells, which can renew and proliferate in culture.

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Bibliographische Detailangaben
Hauptverfasser: Hammer, Robert E, Hamra, Franklin Kent, Cronkhite, Jennifer T
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A transgenic rat expresses a gene of interest, such as EGFP, exclusively in the germ cells of both males and females. From such a transgenic rat one can isolate a line of spermatogonial stem cells, which can renew and proliferate in culture.