Azolylacylguanidines as β-secretase inhibitors

The present invention provides an azolylacylquanidine compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

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Bibliographische Detailangaben
Hauptverfasser:	Cole, Derek Cecil, Manas, Eric Steven, Jennings, Lee Dalton, Lovering, Frank Eldridge, Stock, Joseph Raymond, Moore, William Jay, Ellingboe, John Watson, Condon, Jeffrey Scott, Sukhdeo, Mohani Nirmala, Zhou, Ping, Wu, Junjun, Morris, Koi Michele
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides an azolylacylquanidine compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.