Derivatives of 4-(imidazol-5-yl)-2-(4-sulfoanilino)pyrimidine with CDK inhibitory activity

12345 Compounds of the formula (I): wherein R, R, R, R, Rand p are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell c...

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Bibliographische Detailangaben
Hauptverfasser: Newcombe, Nicholas John, Thomas, Andrew Peter
Format: Patent
Sprache:eng
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Zusammenfassung:12345 Compounds of the formula (I): wherein R, R, R, R, Rand p are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.