Signal sequences for preparing leu-hirudin by secretion by

XX X E coliE coli. The present invention relates to a efficient expression of a protein, particularly, hirudin; a protein precursor comprising a signal sequence and the sequence of aa-hirudin, wherein aais a selected amino acid, and aais preferably leucine; to its preparation and use; and to process...

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Bibliographische Detailangaben
Hauptverfasser: Habermann, Paul, Bender, Rudolf
Format: Patent
Sprache:eng
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Zusammenfassung:XX X E coliE coli. The present invention relates to a efficient expression of a protein, particularly, hirudin; a protein precursor comprising a signal sequence and the sequence of aa-hirudin, wherein aais a selected amino acid, and aais preferably leucine; to its preparation and use; and to processes for finding signal sequences for secretory expression of any desired protein in ; and to processes for the secretory expression of any desired protein in