Amlodipine gentisate and a method of its preparation

The present invention relates to an acid salt of amlodipine gentisate and a method of its preparation. More particularly, the present invention relates to a crystalline acid salt of amlodipine gentisate of the following formula 1 prepared by reacting amlodipine and gentisic acid, which is useful for...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kim, Jae-Sun, Choi, Jin Young, Ryu, Je Ho, Lee, Nam Kyu, Jang, Jeong-soo, Jang, Woo Jae, Um, Key An, Kum, Do Seung
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Kim, Jae-Sun
Choi, Jin Young
Ryu, Je Ho
Lee, Nam Kyu
Jang, Jeong-soo
Jang, Woo Jae
Um, Key An
Kum, Do Seung
description The present invention relates to an acid salt of amlodipine gentisate and a method of its preparation. More particularly, the present invention relates to a crystalline acid salt of amlodipine gentisate of the following formula 1 prepared by reacting amlodipine and gentisic acid, which is useful for the treatment of cardiovascular diseases and has the advantages of low toxicity, excellent stability, improved pharmaceutical efficacies and long-lasting concentration in blood.
format Patent
fullrecord <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_07442714</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>07442714</sourcerecordid><originalsourceid>FETCH-uspatents_grants_074427143</originalsourceid><addsrcrecordid>eNrjZDBxzM3JT8ksyMxLVUhPzSvJLE4sSVVIzEtRSFTITS3JyE9RyE9TyCwpVigoSi1ILEosyczP42FgTUvMKU7lhdLcDApuriHOHrqlxQVA7XklxfHpRYkgysDcxMTI3NDEmAglAPJXLYg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Amlodipine gentisate and a method of its preparation</title><source>USPTO Issued Patents</source><creator>Kim, Jae-Sun ; Choi, Jin Young ; Ryu, Je Ho ; Lee, Nam Kyu ; Jang, Jeong-soo ; Jang, Woo Jae ; Um, Key An ; Kum, Do Seung</creator><creatorcontrib>Kim, Jae-Sun ; Choi, Jin Young ; Ryu, Je Ho ; Lee, Nam Kyu ; Jang, Jeong-soo ; Jang, Woo Jae ; Um, Key An ; Kum, Do Seung ; SK Chemicals Co., Ltd</creatorcontrib><description>The present invention relates to an acid salt of amlodipine gentisate and a method of its preparation. More particularly, the present invention relates to a crystalline acid salt of amlodipine gentisate of the following formula 1 prepared by reacting amlodipine and gentisic acid, which is useful for the treatment of cardiovascular diseases and has the advantages of low toxicity, excellent stability, improved pharmaceutical efficacies and long-lasting concentration in blood.</description><language>eng</language><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7442714$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7442714$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Kim, Jae-Sun</creatorcontrib><creatorcontrib>Choi, Jin Young</creatorcontrib><creatorcontrib>Ryu, Je Ho</creatorcontrib><creatorcontrib>Lee, Nam Kyu</creatorcontrib><creatorcontrib>Jang, Jeong-soo</creatorcontrib><creatorcontrib>Jang, Woo Jae</creatorcontrib><creatorcontrib>Um, Key An</creatorcontrib><creatorcontrib>Kum, Do Seung</creatorcontrib><creatorcontrib>SK Chemicals Co., Ltd</creatorcontrib><title>Amlodipine gentisate and a method of its preparation</title><description>The present invention relates to an acid salt of amlodipine gentisate and a method of its preparation. More particularly, the present invention relates to a crystalline acid salt of amlodipine gentisate of the following formula 1 prepared by reacting amlodipine and gentisic acid, which is useful for the treatment of cardiovascular diseases and has the advantages of low toxicity, excellent stability, improved pharmaceutical efficacies and long-lasting concentration in blood.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZDBxzM3JT8ksyMxLVUhPzSvJLE4sSVVIzEtRSFTITS3JyE9RyE9TyCwpVigoSi1ILEosyczP42FgTUvMKU7lhdLcDApuriHOHrqlxQVA7XklxfHpRYkgysDcxMTI3NDEmAglAPJXLYg</recordid><startdate>20081028</startdate><enddate>20081028</enddate><creator>Kim, Jae-Sun</creator><creator>Choi, Jin Young</creator><creator>Ryu, Je Ho</creator><creator>Lee, Nam Kyu</creator><creator>Jang, Jeong-soo</creator><creator>Jang, Woo Jae</creator><creator>Um, Key An</creator><creator>Kum, Do Seung</creator><scope>EFH</scope></search><sort><creationdate>20081028</creationdate><title>Amlodipine gentisate and a method of its preparation</title><author>Kim, Jae-Sun ; Choi, Jin Young ; Ryu, Je Ho ; Lee, Nam Kyu ; Jang, Jeong-soo ; Jang, Woo Jae ; Um, Key An ; Kum, Do Seung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_074427143</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2008</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Kim, Jae-Sun</creatorcontrib><creatorcontrib>Choi, Jin Young</creatorcontrib><creatorcontrib>Ryu, Je Ho</creatorcontrib><creatorcontrib>Lee, Nam Kyu</creatorcontrib><creatorcontrib>Jang, Jeong-soo</creatorcontrib><creatorcontrib>Jang, Woo Jae</creatorcontrib><creatorcontrib>Um, Key An</creatorcontrib><creatorcontrib>Kum, Do Seung</creatorcontrib><creatorcontrib>SK Chemicals Co., Ltd</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Kim, Jae-Sun</au><au>Choi, Jin Young</au><au>Ryu, Je Ho</au><au>Lee, Nam Kyu</au><au>Jang, Jeong-soo</au><au>Jang, Woo Jae</au><au>Um, Key An</au><au>Kum, Do Seung</au><aucorp>SK Chemicals Co., Ltd</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Amlodipine gentisate and a method of its preparation</title><date>2008-10-28</date><risdate>2008</risdate><abstract>The present invention relates to an acid salt of amlodipine gentisate and a method of its preparation. More particularly, the present invention relates to a crystalline acid salt of amlodipine gentisate of the following formula 1 prepared by reacting amlodipine and gentisic acid, which is useful for the treatment of cardiovascular diseases and has the advantages of low toxicity, excellent stability, improved pharmaceutical efficacies and long-lasting concentration in blood.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_grants_07442714
source USPTO Issued Patents
title Amlodipine gentisate and a method of its preparation
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T02%3A25%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Kim,%20Jae-Sun&rft.aucorp=SK%20Chemicals%20Co.,%20Ltd&rft.date=2008-10-28&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E07442714%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true