5-HT

1 4 1-6 3-7 3-7 1-4 1-4 1 4 9-14 2 3 22n565 6 1-4 1-4 5-7 2B The present invention relates to compounds of formula I: wherein one of Rand Ris selected from the group consisting of H, and optionally substituted Calkyl, Ccycloalkyl, Ccycloalkyl-Calkyl, and phenyl-Calkyl; and the other of Rand Ris an optionally substituted Caryl group; Rand Rare either: (i) independently selected from H, R, R′, SOR, C(═O)R, (CH)NRR, where n is from 1 to 4 and Rand Rare independently selected from H and R, where R is optionally substituted Calkyl, and R′ is optionally substituted phenyl-Calkyl, or (ii) together with the nitrogen atom to which they are attached, form an optionally substituted Cheterocyclic group; and their use as pharmaceuticals, in particular for treating conditions alleviated by the antagonism of a 5-HTreceptor.