Piperazine urea derivatives as melanocortin-4 receptor agonists

Piperazine urea derivatives as melanocortin-4 receptor agonists

Certain novel piperazine urea derivatives are agonists of the human melanocortin-4 receptor (MC-4R) and, in particular, are receptor-subtype selective agonists of MC-4R. They are useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as...

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Hauptverfasser: Bakshi, Raman Kumar, Nargund, Ravi P, Palucki, Brenda L, Park, Min K, Ye, Zhixiong
Format: Patent
Sprache:eng
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Zusammenfassung:Certain novel piperazine urea derivatives are agonists of the human melanocortin-4 receptor (MC-4R) and, in particular, are receptor-subtype selective agonists of MC-4R. They are useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity and diabetes.