2-(arylalkoxy)-1-phenylethylamine derivatives as NK

1 21 2 1 Compounds of the following formula (I) wherein RR, n, Arand Aare as defined in the specification, in vivo-hydrolysable precursors thereof, pharmaceutically acceptable salts thereof, the use in therapy and pharmaceutical compositions and methods of treatment using the same. The example compo...

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1. Verfasser: Dantzman, Cathy
Format: Patent
Sprache:eng
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Zusammenfassung:1 21 2 1 Compounds of the following formula (I) wherein RR, n, Arand Aare as defined in the specification, in vivo-hydrolysable precursors thereof, pharmaceutically acceptable salts thereof, the use in therapy and pharmaceutical compositions and methods of treatment using the same. The example compounds are 1-(2-(naphthylmethoxy)-1-phenylethyl)piperazine derivatives. The compounds are neurokinin 1 (NK) receptor antagonist and/or serotonin reuptake inhibitors, with medical indications for depression and other disorders