Human neutralizing monoclonal antibodies to respiratory syncytial virus

Human monoclonal antibodies and fragments thereof which bind, neutralize and provide passive immunotherapy to respiratory syncytial virus (RSV) antigenic subgroups A and B are disclosed. Also disclosed are diagnostic and immunotherapeutic methods of using the monoclonal antibodies as well as cell li...

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Bibliographische Detailangaben
Hauptverfasser: Burton, Dennis R, Barbas, III, Carlos F, Chanock, Robert M, Murphy, Brian R, Crowe, Jr, James E
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Human monoclonal antibodies and fragments thereof which bind, neutralize and provide passive immunotherapy to respiratory syncytial virus (RSV) antigenic subgroups A and B are disclosed. Also disclosed are diagnostic and immunotherapeutic methods of using the monoclonal antibodies as well as cell line producing the monoclonal antibodies.