Cytotoxicity mediation of cells evidencing surface expression of CD63

This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a mean...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Young, David S. F, Hahn, Susan E, Findlay, Helen P, da Cruz, Luis A. G
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.