Process for regenerating 2-chlorotrityl resins

The present invention relates to a recycling process for the preparation of solid phase bonded 2-chlorotrityl chloride (2-CTC resin) useful for solid phase peptide synthesis, wherein active chloride CTC resin is regenerated by reacting the spent resin with a chlorinating agent in organic solvent.

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Bibliographische Detailangaben
Hauptverfasser: Barlos, Kleomenis, Knipp, Bernhard
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a recycling process for the preparation of solid phase bonded 2-chlorotrityl chloride (2-CTC resin) useful for solid phase peptide synthesis, wherein active chloride CTC resin is regenerated by reacting the spent resin with a chlorinating agent in organic solvent.