Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them

312 The present invention provides a compound of the following formula I: R-NH-C(═X)-P(═O)OROR including pharmaceutically acceptable salts, solvates, hydrates and polymorphs of the compounds of formula I, as well as geometrical isomers and optically active forms of the compounds of formula I and pharmaceutically acceptable salts, solvates, hydrates and polymorphs of said isomers and forms, wherein The invention further provides pharmaceutical compositions comprising the above compounds and their use in medicine.