Recombinant immunogens for the generation of antivenoms to the venom of scorpions of the genus

CentruroidesThe invention concerns genes and fusion of genes that code for scorpion toxins and the corresponding polypeptides. The invention also concerns the use of the polypeptides as immunogens for the generation of antibodies that can recognize and neutralize components of scorpion venom as well...

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Bibliographische Detailangaben
Hauptverfasser:	Corona Villegas, Miguel, Garcia Rodríguez, Ma Consuelo, Gurrola Briones, Georgina, Valdez Cruz, Norma Adriana, Becerril Luján, Baltazar, Possani Postay, Lourival Domingos
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	CentruroidesThe invention concerns genes and fusion of genes that code for scorpion toxins and the corresponding polypeptides. The invention also concerns the use of the polypeptides as immunogens for the generation of antibodies that can recognize and neutralize components of scorpion venom as well as for vaccines to prevent envenomation from stings of scorpions of the genus , and to immunogenic matrices for the purification of specific immunoglobulins.