Jun kinase inhibitors

The present invention provides novel compounds of formula I and their use in the inhibition of c-Jun N-terminal kinases. The present invention further provides the use of these compounds in medicine, in particular in the prevention and/or treatment of neurodegenerative disorders related to apoptosis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Graczyk, Piotr, Numata, Hirotoshi, Khan, Afzal, Palmer, Vanessa, Medland, Darren Peter, Oinuma, Hitoshi, Bhatia, Gurpreet
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides novel compounds of formula I and their use in the inhibition of c-Jun N-terminal kinases. The present invention further provides the use of these compounds in medicine, in particular in the prevention and/or treatment of neurodegenerative disorders related to apoptosis and/or inflammation.