Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses

The present invention discloses novel substituted aryl alkylamine compounds of Formula (I) or pharmaceutically acceptable salts thereof which have selective histamine-H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharm...

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Bibliographische Detailangaben
Hauptverfasser: Beavers, Lisa Selsam, Gadski, Robert Alan, Hipskind, Philip Arthur, Lindsley, Craig William, Lobb, Karen Lynn, Nixon, James Arthur, Pickard, Richard Todd, Schaus, John Mehnert, Takakuwa, Takako, Watson, Brian Morgan
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention discloses novel substituted aryl alkylamine compounds of Formula (I) or pharmaceutically acceptable salts thereof which have selective histamine-H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such cyclic amines as well as methods of using them to treat obesity and other histamine H3 receptor-related diseases