1-[(indol-3-yl)carbonyl]piperazine derivatives

The present invention relates to 1-[(indol-3-yl)carbonyl]piperazine derivative according to the general formula I or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said 1-[(indol-3-yl)carbonyl]piperazine derivatives, and to the use of...

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Bibliographische Detailangaben
Hauptverfasser: Cowley, Phillip Martin, Caulfield, Wilson, Tierney, Jason, Cairns, James, Adam-Worrall, Julia, York, Mark
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to 1-[(indol-3-yl)carbonyl]piperazine derivative according to the general formula I or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said 1-[(indol-3-yl)carbonyl]piperazine derivatives, and to the use of these derivatives in the treatment of pain, such as peri-operative pain, chronic pain neuropathic pain, cancer pain, and pain and spasticity associated with multiple sclerosis.