Substituted aryl amides as IP antagonists

Substituted aryl amides as IP antagonists

123 4 Compounds effective as IP receptor modulators, particularly IP receptor antagonists, that are of the formula I: wherein A, R, R, Rand Rare as defined in the specification; and individual isomers, racemic or non-racemic mixtures of isomers, and pharmaceutically acceptable salts or solvates ther...

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Bibliographische Detailangaben
Hauptverfasser: Keitz, Paul Francis, Jahangir, Alam, Lopez-Tapia, Francisco Javier, O'Yang, Counde
Format: Patent
Sprache:eng
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Zusammenfassung:123 4 Compounds effective as IP receptor modulators, particularly IP receptor antagonists, that are of the formula I: wherein A, R, R, Rand Rare as defined in the specification; and individual isomers, racemic or non-racemic mixtures of isomers, and pharmaceutically acceptable salts or solvates thereof. Also disclosed are pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents.