Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
123 4 Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula 1, wherein the substituents R, R, Rand Rhave the meanings given in the description and also pharmaceutical compositions containing these compounds, in particu...
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| creator | Hoeltje, Dagmar Fischer, Yvan Ziegler, Dieter Weske, Michael Michaelis, Katrin Karimi-Nejad, Yasmin Messinger, Josef Pahl, Axel Hoefer, Constanze Ikonomidou, Hrissanthi Turski, Lechoslaw |
| description | 123 4 Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula 1, wherein the substituents R, R, Rand Rhave the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis. |
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Fischer, Yvan ; Ziegler, Dieter ; Weske, Michael ; Michaelis, Katrin ; Karimi-Nejad, Yasmin ; Messinger, Josef ; Pahl, Axel ; Hoefer, Constanze ; Ikonomidou, Hrissanthi ; Turski, Lechoslaw</creator><creatorcontrib>Hoeltje, Dagmar ; Fischer, Yvan ; Ziegler, Dieter ; Weske, Michael ; Michaelis, Katrin ; Karimi-Nejad, Yasmin ; Messinger, Josef ; Pahl, Axel ; Hoefer, Constanze ; Ikonomidou, Hrissanthi ; Turski, Lechoslaw ; Solvay Pharmaceuticals GmbH</creatorcontrib><description>123 4 Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula 1, wherein the substituents R, R, Rand Rhave the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.</description><language>eng</language><creationdate>2007</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7262184$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64038</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7262184$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Hoeltje, Dagmar</creatorcontrib><creatorcontrib>Fischer, Yvan</creatorcontrib><creatorcontrib>Ziegler, Dieter</creatorcontrib><creatorcontrib>Weske, Michael</creatorcontrib><creatorcontrib>Michaelis, Katrin</creatorcontrib><creatorcontrib>Karimi-Nejad, Yasmin</creatorcontrib><creatorcontrib>Messinger, Josef</creatorcontrib><creatorcontrib>Pahl, Axel</creatorcontrib><creatorcontrib>Hoefer, Constanze</creatorcontrib><creatorcontrib>Ikonomidou, Hrissanthi</creatorcontrib><creatorcontrib>Turski, Lechoslaw</creatorcontrib><creatorcontrib>Solvay Pharmaceuticals GmbH</creatorcontrib><title>Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them</title><description>123 4 Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula 1, wherein the substituents R, R, Rand Rhave the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2007</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNjUFOAzEMRWfDAgF38JJKRKKlgm4RArFixR55ErdjkThR7EhML8mVyBQOwOrL_s_P58P3Y-KQE9k0R6dtVGNrRgHW7tpjHfPXjPFzjivws4-5kFgHT43MERNLdiPJEY9UWMi9OfRk7AE9B_A5ldwk6A2Umj2pAkoAFqOaKDAaLUVo3hT2uYJNxLWvqGBF4ywnvkxYU_e2Lsb4a1Veau2DGLKwHJbjdDmc7TEqXf3lxQAvz-9Pr65p6d_E9ONQcYnbh839Zr3b3v0D-QEup2or</recordid><startdate>20070828</startdate><enddate>20070828</enddate><creator>Hoeltje, Dagmar</creator><creator>Fischer, Yvan</creator><creator>Ziegler, Dieter</creator><creator>Weske, Michael</creator><creator>Michaelis, Katrin</creator><creator>Karimi-Nejad, Yasmin</creator><creator>Messinger, Josef</creator><creator>Pahl, Axel</creator><creator>Hoefer, Constanze</creator><creator>Ikonomidou, Hrissanthi</creator><creator>Turski, Lechoslaw</creator><scope>EFH</scope></search><sort><creationdate>20070828</creationdate><title>Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them</title><author>Hoeltje, Dagmar ; 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| title | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them |
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