Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them

Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them

123 4 Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula 1, wherein the substituents R, R, Rand Rhave the meanings given in the description and also pharmaceutical compositions containing these compounds, in particu...

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Hauptverfasser: Hoeltje, Dagmar, Fischer, Yvan, Ziegler, Dieter, Weske, Michael, Michaelis, Katrin, Karimi-Nejad, Yasmin, Messinger, Josef, Pahl, Axel, Hoefer, Constanze, Ikonomidou, Hrissanthi, Turski, Lechoslaw
Format: Patent
Sprache:eng
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Zusammenfassung:123 4 Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula 1, wherein the substituents R, R, Rand Rhave the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.