Amidino compounds useful as nitric oxide synthase inhibitors

Amidino compounds useful as nitric oxide synthase inhibitors

The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of m...

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Hauptverfasser: Webber, Ronald Keith, Durley, Richard C, Awasthi, Alok K, Bergmanis, Arija A, Fok, Kam F, Ganser, Scott S, Hagen, Timothy J, Hallinan, E. Ann, Hansen, Jr, Donald W, Hickory, Brian S, Manning, Pamela T, Mao, Michael, Moormann, Alan E, Pitzele, Barnett S, Promo, Michelle A, Schartman, Richard R, Scholten, Jeffrey A, Snyder, Jeffrey S, Toth, Mihaly V, Trivedi, Mahima, Tsymbalov, Sofya, Tjoeng, Foe Siong
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of making the amidino compounds.