Mutant

Actinosynnema pretiosumA microorganism that is a mutant bacterial strain of the species , designated PF4-4, (ATCC PTA-3921), being capable of producing maytansinoid ansamitocins such as ansamitocin P-3 in improved yield compared to previous known strains, and capable of growth under varied culture c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chung, Johnson, Byng, Graham S
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Actinosynnema pretiosumA microorganism that is a mutant bacterial strain of the species , designated PF4-4, (ATCC PTA-3921), being capable of producing maytansinoid ansamitocins such as ansamitocin P-3 in improved yield compared to previous known strains, and capable of growth under varied culture conditions, and methods of producing maytansinoid ansamitocins by culturing PF4-4 in a suitable growth medium.