Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (Montelukast) and its pharmaceutically acceptable salts

Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (Montelukast) and its pharmaceutically acceptable salts

2The present invention is related to a process for preparing montelukast involving the compound of formula (VI): wherein X═CN or CONH.

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Bibliographische Detailangaben
Hauptverfasser: Sundaram, Venkataraman, Rajan, Srinivasan Thirumalai, Bulusu, Veera Venkata Naga Chandra Sekhar, Srivastav, AlokKumar, Kasturi, Ravi Kumar, Aavula, Sanjeev Kumar
Format: Patent
Sprache:eng
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Zusammenfassung:2The present invention is related to a process for preparing montelukast involving the compound of formula (VI): wherein X═CN or CONH.