Method for characterizing autoimmune disorders

The invention relates to methods of characterizing autoimmune diseases by detecting and measuring at least one analyte using multiplexed assay systems. According to one embodiment, a target is detected and measured by different bead sets having different reactants. According to another approach the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mapes, James P, Jacobson, James W, Baker, Harold N, Spain, Michael D
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to methods of characterizing autoimmune diseases by detecting and measuring at least one analyte using multiplexed assay systems. According to one embodiment, a target is detected and measured by different bead sets having different reactants. According to another approach the ratio of self-antigen to autoantibody is measured by exposing a sample suspected of containing self-antigen and autoantibody to a bead set associated with monoclonal antibody specific for the self-antigen and a bead set associated with the self-antigen.