Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents
1 2 1 1 1 2 3 1 2 Compounds of formula (I), wherein Gis CH or N; Gis CH or N; Ris a variety of optional substituents; Lis (1-4C)alkylene; Tis CH or N; Rand Rare independently hydrogen or (1-4C)alkyl or are joined to form a ring; Xand Xrepresent various linking groups; Ar is phenylene or certain hete...
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Zusammenfassung: | 1 2 1 1 1 2 3 1 2 Compounds of formula (I), wherein Gis CH or N; Gis CH or N; Ris a variety of optional substituents; Lis (1-4C)alkylene; Tis CH or N; Rand Rare independently hydrogen or (1-4C)alkyl or are joined to form a ring; Xand Xrepresent various linking groups; Ar is phenylene or certain heteroaryl rings and Q represents a variety of aromatic or heterocyclic rings systems, and pharmaceutically acceptable salts thereof are described as useful antithrombotic and anticoagulant agents, and are selective Factor Xa inhibitors. Processes for their preparation and pharmaceutical compositions containing them are also described. |
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