1,2,4-oxadiazole derivatives as hPPAR alpha agonists

1,2,4-oxadiazole derivatives as hPPAR alpha agonists

1 2 1 2 33 1-3 3 31-6 4 5 1-3 A compound of formula (I) and pharmaceutically acceptable salts, solvates and hydrolysable esters thereof wherein: Xis O or S; Xis O or S; n is 1-3, One of Y and Z is N, and the other is O; Rand Rare independently halogen, H, CH, OCHor Calkyl; Each Rindependently is hal...

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Hauptverfasser: Gellibert, Françoise Jeanne, Liu, Kevin Guangcheng
Format: Patent
Sprache:eng
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Zusammenfassung:1 2 1 2 33 1-3 3 31-6 4 5 1-3 A compound of formula (I) and pharmaceutically acceptable salts, solvates and hydrolysable esters thereof wherein: Xis O or S; Xis O or S; n is 1-3, One of Y and Z is N, and the other is O; Rand Rare independently halogen, H, CH, OCHor Calkyl; Each Rindependently is halogen, CF, Cstraight or branched alkyl; Rand Rare independently H or Calkyl. y is 0, 1, 2, 3, 4 or 5.