Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives

1 2 3 4 5 Disclosed are the compounds of formula I wherein R is methyl or ethyl; Ris chloro or fluoro; Ris hydrogen or fluoro; Ris hydrogen, fluoro, chloro, methyl, ethyl, methoxy, ethoxy or hydroxy; Ris hydrogen or fluoro; and Ris chloro, fluoro, trifluoromethyl or methyl; and pharmaceutically acce...

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Bibliographische Detailangaben
Hauptverfasser:	Fujimoto, Roger A, McQuire, Leslie W, Mugrage, Benjamin B, Van Duzer, John H, Xu, Daqiang
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	1 2 3 4 5 Disclosed are the compounds of formula I wherein R is methyl or ethyl; Ris chloro or fluoro; Ris hydrogen or fluoro; Ris hydrogen, fluoro, chloro, methyl, ethyl, methoxy, ethoxy or hydroxy; Ris hydrogen or fluoro; and Ris chloro, fluoro, trifluoromethyl or methyl; and pharmaceutically acceptable salts thereof, as selective COX-2 cyclooxygenase inhibitors; and pharmaceutically acceptable prodrug esters thereof.