Thiazole compounds as integrin receptor antagonists derivatives

v3 v5 v6 The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the αβand/or the αβintegrin without sign...

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Bibliographische Detailangaben
Hauptverfasser: Wendt, John A, Stenmark, Heather, Wu, Hongwei, Wang, Yaping, Chen, Barbara B, Penning, Thomas D, Downs, Victoria L, Boys, Mark L, Russell, Mark, Spangler, Dale P
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:v3 v5 v6 The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the αβand/or the αβintegrin without significantly inhibiting the αβintegrin.