Methods of making amidino compounds useful as nitric oxide synthase inhibitors

Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33: where the substituents are described herein.

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Hauptverfasser: Webber, Ronald Keith, Durley, Richard C, Awasthi, Alok K, Bergmanis, Arija A, Fok, Kam F, Ganser, Scott S, Hagen, Timothy J, Hallinan, E. Ann, Hansen, Jr, Donald W, Hickory, Brian S, Manning, Pamela T, Mao, Michael, Moormann, Alan E, Pitzele, Barnett S, Promo, Michelle A, Schartman, Richard R, Scholten, Jeffrey A, Snyder, Jeffrey S, Toth, Mihaly V, Trivedi, Mahima, Tsymbalov, Sofya, Tjoeng, Foe Siong
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creator Webber, Ronald Keith
Durley, Richard C
Awasthi, Alok K
Bergmanis, Arija A
Fok, Kam F
Ganser, Scott S
Hagen, Timothy J
Hallinan, E. Ann
Hansen, Jr, Donald W
Hickory, Brian S
Manning, Pamela T
Mao, Michael
Moormann, Alan E
Pitzele, Barnett S
Promo, Michelle A
Schartman, Richard R
Scholten, Jeffrey A
Snyder, Jeffrey S
Toth, Mihaly V
Trivedi, Mahima
Tsymbalov, Sofya
Tjoeng, Foe Siong
description Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33: where the substituents are described herein.
format Patent
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title Methods of making amidino compounds useful as nitric oxide synthase inhibitors
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