Methods of making amidino compounds useful as nitric oxide synthase inhibitors

Methods of making amidino compounds useful as nitric oxide synthase inhibitors

Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33: where the substituents are described herein.

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Bibliographische Detailangaben
Hauptverfasser: Webber, Ronald Keith, Durley, Richard C, Awasthi, Alok K, Bergmanis, Arija A, Fok, Kam F, Ganser, Scott S, Hagen, Timothy J, Hallinan, E. Ann, Hansen, Jr, Donald W, Hickory, Brian S, Manning, Pamela T, Mao, Michael, Moormann, Alan E, Pitzele, Barnett S, Promo, Michelle A, Schartman, Richard R, Scholten, Jeffrey A, Snyder, Jeffrey S, Toth, Mihaly V, Trivedi, Mahima, Tsymbalov, Sofya, Tjoeng, Foe Siong
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33: where the substituents are described herein.