Peptide fragmentation

The present invention relates to a method of identifying a polypeptide using a class of novel, water-stable reagents. More specifically, the method according to the invention comprises the steps of Furthermore, the present invention also relates to a kit for identifying a polypeptide by a mass spect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Palmgren, Ronnie, Maloisel, Jean-Luc, Liminga, Maria, Keough, Thomas Woods, Youngquist, Robert Scott
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a method of identifying a polypeptide using a class of novel, water-stable reagents. More specifically, the method according to the invention comprises the steps of Furthermore, the present invention also relates to a kit for identifying a polypeptide by a mass spectrometric technique, which kit comprises at least one acidic reagent comprising a sulfonyl moiety coupled to an activated acid moiety in a container together with suitable means for analysis of the fragmentation pattern obtained.