Pyrimidine derivatives as selective inhibitors of COX-2

Pyrimidine derivatives as selective inhibitors of COX-2

The invention provides the compounds of formula (I) and pharmaceutically acceptable salts thereof, in which: Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever, inflammation of a variety of conditions and diseases.

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Bibliographische Detailangaben
Hauptverfasser: Carter, Malcolm C, Naylor, Alan, Payne, Jeremy J, Pegg, Neil A
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides the compounds of formula (I) and pharmaceutically acceptable salts thereof, in which: Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever, inflammation of a variety of conditions and diseases.