Inclusion complex of Rifampicin, an anti-tubercular drug, with β-cyclodextrin or 2-hydroxypropyl β-cyclodextrin and a process thereof

Inclusion complex of Rifampicin, an anti-tubercular drug, with β-cyclodextrin or 2-hydroxypropyl β-cyclodextrin and a process thereof

The present invention relates to an inclusion complex of Rifampicin and cyclodextrin (CD) that can be used as an anti-tubercular drug. The present invention also relates to a process for synthesizing inclusion complexes of the anti-tubercular drug, Rifampicin, with β-CD (β-cyclodextrin) and HP-β-CD...

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Bibliographische Detailangaben
Hauptverfasser: Rao, Kakulapati Rama, Bhanumathi, Nanduri, Yadav, Jhillu Singh, Krishnaveni, Neelam Srilakshmi
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to an inclusion complex of Rifampicin and cyclodextrin (CD) that can be used as an anti-tubercular drug. The present invention also relates to a process for synthesizing inclusion complexes of the anti-tubercular drug, Rifampicin, with β-CD (β-cyclodextrin) and HP-β-CD (2-hydroxy propyl cyclodextrin) and characterization of these inclusion complexes.